Bio-Connect

GSTM3 Polyclonal Antibody

Research Use Only
RD266409A
Reddot Biotech
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman
TargetGSTM3
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Reddot Biotech
  • Product Name
    GSTM3 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2947
  • Target name
    GSTM3
  • Target description
    glutathione S-transferase mu 3
  • Target synonyms
    brain GST; brain type mu-glutathione S-transferase; epididymis secretory sperm binding protein; glutathione S-alkyltransferase M3; glutathione S-aralkyltransferase M3; glutathione S-aryltransferase M3; glutathione S-transferase M3 (brain); glutathione S-transferase Mu 3; glutathione S-transferase mu 3 (brain); glutathione S-transferase, Mu-3; GST class-mu 3; GST5; GSTB; GSTM3-3; GTM3; hGSTM3-3; S-(hydroxyalkyl)glutathione lyase M3
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individuals susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203