GW1929 (hydrochloride) [1217466-21-1]

MedChem Express

GW1929 (hydrochloride) [1217466-21-1]

10

1217466-21-1

Research Use Only

C30H30ClN3O4

532.03

GW1929 hydrochloride is an orally active peroxisome proliferator-activated receptor-gamma (PPARgamma) agonist with a pKi of 8.84 for human PPAR-gamma, and pEC50s of 8.56 and 8.27 for human PPAR-gamma and murine PPAR-gamma, respectively. GW1929 hydrochloride has antidiabetic efficacy and neuroprotective potential. GW1929 hydrochloride suppresses neuronal apoptosis and shows anti-inflammatory potential[1][2][3].

O=C(C1=CC=CC=C1)C2=C(C=CC=C2)N[C@H](C(O)=O)CC3=CC=C(C=C3)OCCN(C4=CC=CC=N4)C.Cl

12352200