GW2580-d6

MedChem Express

GW2580-d6 [2733770-48-2]

5

2733770-48-2

Research Use Only

98.36

C20H16D6N4O3

372.45

GW2580-d6 is the deuterium labeled GW2580. GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 microM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling [1] .

NC1=NC(N)=C(CC2=CC(OC([2H])([2H])[2H])=C(OCC3=CC=C(OC([2H])([2H])[2H])C=C3)C=C2)C=N1

-20°C,2°C to 8°C

12352200