GW549390X [135307-33-4]

TargetMol Chemicals

GW549390X [135307-33-4]

16

Research Use Only

C15H12N2O

236.27

GW549390X is a dual inhibitor targeting both Fluc and VEGFR2, with IC50 values of 0.26 microM and 1.2 microM, respectively. This compound binds to the ATP pocket of FLuc via the aniline side chain, functioning as an ATP-competitive inhibitor of Fluc. It serves as a protein kinase inhibitor across ATP-dependent and -independent luciferases, potentially affecting Fluc reporter assays [1].

N(C=1OC(=CN1)C2=CC=CC=C2)C3=CC=CC=C3

-20°C

12352200