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GW806742X

M8758
AbMole BioScience
CAS Number579515-63-2
Product group Chemicals
Molecular Weight573.55
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    GW806742X
  • Delivery Days Customer
    9
  • CAS Number
    579515-63-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C25H22F3N7O4S
  • Molecular Weight
    573.55
  • Scientific Description
    GW806742X is an ATP site-targeing kinase inhibitor (IC50 in nM = 2/VEGFR2, 15/SRC, 47/C-FMS, 851/GSK3, 9016/ERBB2, 9120/FGFR) with potent antiproliferation activity against cancer cultures (IC50 in nM = 5/HUVEC-v, 424/HUVEC-b, 81/HEF, 453/MDA468, 470/A375P, 693/HT29, 734/PC3), GW806742X is now better known as Compound 1 for its anti-necroptosis activity via affinity interaction with ML
  • SMILES
    CN(C1=CC=C(NC(=O)NC2=CC=C(OC(F)(F)F)C=C2)C=C1)C3=NC(=NC=C3)NC4=CC(=CC=C4)[S](N)(=O)=O
  • Storage Instruction
    4°C, dry, sealed
  • UNSPSC
    12352200

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