GW814408X [886599-05-9]

TargetMol Chemicals

GW814408X [886599-05-9]

16

Research Use Only

C19H16N6O

344.37

GW814408X, a kinase chemical genome group (KCGS) compound, inhibits the AURKC kinase, which is involved in cell cycle progression, checkpoint regulation, and cell division. It exhibits cell line-dependent toxicity, such as cytotoxic effects on HeLa cells, and acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases, potentially impacting Fluc reporter assays [1].

N(N=CC=1C=CN=CC1)C2=C3C(C(=CN3)C4=CC(OC)=CC=C4)=NC=N2

-20°C

12352200