GW9508

MedChem Express

GW9508 [885101-89-3]

10

885101-89-3

Research Use Only

99.33

C22H21NO3

347.41

GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC 50 s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120 . GW9508 is inactive against other GPCRs, kinases, proteases, integrins and PPARs. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (K ATP ) channels opener. Anti-inflammatory and anti-atherosclerotic activities [1] [2] [3] [4] .

O=C(O)CCC1=CC=C(NCC2=CC=CC(OC3=CC=CC=C3)=C2)C=C1

-20°C,2°C to 8°C

12352200