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GX-674 [1432913-36-4]

GX-674 [1432913-36-4]

Research Use Only
T22829
TargetMol Chemicals
Molecular Weight534.95
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GX-674 [1432913-36-4]
  • Delivery Days Customer
    72
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    GX-674
  • Molecular Formula
    C21H13ClF2N6O3S2
  • Molecular Weight
    534.95
  • Scientific Description
    GX-674 is a highly potent and selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 value of 0.1 nM measured at -40 mV for the study of inflammatory and neuropathic pain.
  • Shelf life instruction
    3 years
  • SMILES
    O(C1=C(C=C(Cl)C=C1)C=2C=C3C(=CC2)N=C(N)N3)C4=C(F)C=C(S(NC5=NC=NS5)(=O)=O)C(F)=C4
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist. Ahuja S et al., 2015 Dec 18, Science
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