GYY 4137

Bioss Antibodies

GYY 4137 [106740-09-4]

16

Research Use Only

>95%

Water-soluble, slow-releasing hydrogen sulfide (H2S) donor [1]. Exhibits vasodilator and antihypertensive activity [1, 2, 4]. Anti-inflammatory [2, 3]. Inhibits LPS-induced release of proinflammatory mediators (IL-1beta, IL-6, TNF-alpha, nitric oxide (NO) and PGE2) and increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-kappaB, ATF-2 and HSP27 dependent pathways [2, 3]. Causes stomatal opening and reduces nitric oxide accumulation in plants [5]. Oxidative stress-induced cell death inhibitor [6]. Shows novel anti-cancer effects in vitro and in vivo [7]. Anti-thrombotic via p-selectin dependent mechanism [8].

-20°C

12352200