Western blot analysis of extracts from NIH/3T3 cells, using Granzyme B antibody.
Western blot analysis of extracts from NIH/3T3 cells, using Granzyme B antibody.
GZMB Antibody
CSB-PA272248
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGZMB
Overview
- SupplierCusabio
- Product NameGZMB Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3002
- Target nameGZMB
- Target descriptiongranzyme B
- Target synonymsC11; cathepsin G-like 1; CCPI; CGL1; CGL-1; CSPB; CSP-B; CTLA1; CTSGL1; cytotoxic serine protease B; cytotoxic T-lymphocyte proteinase 2; fragmentin 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); HLP; human lymphocyte protein; SECT; T-cell serine protease 1-3E
- HostRabbit
- IsotypeIgG
- Protein IDP10144
- Protein NameGranzyme B
- Scientific DescriptionThis enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. David A. Jans, J. Biol. Chem., Nov 1996; 271: 30781. Eugene Estella, Diabetes, Aug 2006; 55: 2212 - 2219. Yong Gu, J. Biol. Chem., May 1996; 271: 10816. Jiuru Sun, J. Biol. Chem., Nov 1996; 271: 27802.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203