H-0106 (dihydrochloride)

MedChem Express

H-0106 (dihydrochloride)

9

Research Use Only

C16H22Cl3N3O2S

426.79

H-0106 dihydrochloride is a ROCK inhibitor with potent intraocular pressure (IOP)-lowering activity. H-0106 dihydrochloride can effectively inhibit ROCK enzyme. H-0106 dihydrochloride demonstrated significant IOP-lowering effects in monkey eyes. Studies with H-0106 dihydrochloride suggest that there may not be a direct relationship between ROCK inhibition and IOP reduction [1] .

O=S(C1=CC=CC2=C1C(Cl)=CN=C2)(N3[C@H](CNCCCC3)C)=O.[H]Cl.[H]Cl

12352200