IHC image of CSB-PA878945LA01HU diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA878945LA01HU diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
HACD3 Antibody
CSB-PA878945LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetHACD3
Overview
- SupplierCusabio
- Product NameHACD3 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID51495
- Target nameHACD3
- Target description3-hydroxyacyl-CoA dehydratase 3
- Target synonymsBIND1; B-IND1; butyrate-induced protein 1; butyrate-induced transcript 1; HSPC121; protein tyrosine phosphatase-like A domain containing 1; protein tyrosine phosphatase-like protein PTPLAD1; protein-tyrosine phosphatase-like A domain-containing protein 1; PTPLAD1; very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 3; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
- HostRabbit
- IsotypeIgG
- Protein IDQ9P035
- Protein NameVery-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3
- Scientific DescriptionCatalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May be involved in Rac1-signaling pathways leading to the modulation of gene expression. Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization (PubMed:25687571).
- Storage Instruction-20°C or -80°C
- UNSPSC12352203
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