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HACE1 Polyclonal Antibody

Research Use Only
RD76862A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetHACE1
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    HACE1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID57531
  • Target name
    HACE1
  • Target description
    HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
  • Target synonyms
    E3 ubiquitin-protein ligase HACE1; HECT-type E3 ubiquitin transferase HACE1; SPPRS
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    HACE1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1), also known as KIAA1320, is a 909 amino acid protein that localizes to both the cytoplasm and the endoplasmic reticulum and contains one HECT domain and six ANK repeats. Expressed in kidney, heart and brain, HACE1 functions as an E3 ubiquitin-protein ligase that interacts with the proteasome and is thought to play a role in protein degradation. HACE1 is downregulated in Wilms tumor, suggesting a possible role in tumor suppression.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203