hAChE-IN-9

MedChem Express

hAChE-IN-9

9

Research Use Only

C20H15ClN6O4S

470.89

hAChE-IN-9 (compound 7i) is a selective inhibitor of human acetylcholinesterase (hAChE) with IC50 of 0.05 microM and 2.85 microM for AChE and BChE, respectively. hAChE-IN-9 modulates toxic Abeta oligomer forms into non-toxic ones and has antioxidant and neuroprotective effects against Abeta-induced toxicity. hAChE-IN-9 can be used for the study of Alzheimers disease[1].

O=C(/C(C#N)=C(SC)/NC1=CC=C([N+]([O-])=O)C=C1)NN2C(CCl)=NC3=CC=CC=C3C2=O

12352200