Anti-Ms TCR beta Purified Low Endotoxin

EXBIO

Hamster Monoclonal to TCR beta (mouse)

7

The Armenian hamster monoclonal antibody H57-597 reacts specifically with an extracellular epitope on beta subunit of TCR alpha/beta. This antibody does not crossreact with TCR gamma/delta type and has been used as TCR alpha/beta phenotypic marker.

Functional application: in vitro T cell stimulation, in vivo T cell depletion. Flow cytometry: Recommended dilution: 1-2 microg/ml per 1 million cells. Immunoprecipitation: Recommended dilution: 1-2 microg / 100-500 microg of protein in 1 ml lysate.

Functional Assay, Flow Cytometry, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

H57-597

1 mg/ml

IgG2b

The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.

Mouse

2°C to 8°C

12352203