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HAUS6 antibody

GTX118732
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetHAUS6
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Overview

  • Supplier
    GeneTex
  • Product Name
    HAUS6 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID54801
  • Target name
    HAUS6
  • Target description
    HAUS augmin like complex subunit 6
  • Target synonyms
    Dgt6; dim gamma-tubulin homolog; FAM29A; family with sequence similarity 29, member A; HAUS augmin-like complex subunit 6
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ7Z4H7
  • Protein Name
    HAUS augmin-like complex subunit 6
  • Scientific Description
    HAUS6 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb augmentare, meaning to increase. The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Microtubule binding of the human augmin complex is directly controlled by importins and Ran-GTP.
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  • Mitotic spindle assembly and gamma-tubulin localisation depend on the integral nuclear membrane protein Samp1. Larsson VJ et al., 2018 Apr 13, J Cell Sci
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  • Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly. Tsai CY et al., 2011 Aug 26, J Biol Chem
    Read more