HBA2 Polyclonal Antibody
RD85091A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityMouse, Rat
TargetHBA1
Overview
- SupplierReddot Biotech
- Product NameHBA2 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3039
- Target nameHBA1
- Target descriptionhemoglobin subunit alpha 1
- Target synonymsalpha globin chain; alpha one globin; alpha-2 globin chain; delta globin; ECYT7; HBA-T3; HBH; hemoglobin alpha 1 globin chain; hemoglobin subunit alpha; hemoglobin, alpha 1; METHBA
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5 untranslated regions and the introns, but they differ significantly over the 3 untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203