HBF-0259 [957011-15-3]

TargetMol Chemicals

HBF-0259 [957011-15-3]

9

957011-15-3

Chemical

Research Use Only

HBF-0259

0.9

C16H12Cl2FN5

364.2

HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 microM and a CC50 value of >50 microM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV-expressing cell line, with a concentration that exhibited 50% cytotoxicity of >50 microM. The equilibrium concentration of HBF-0259 in aqueous solution at physiological pH was 15 to 16 microM; the selective index was thus >9.

3 years

Fc1cccc(Cl)c1C1CC(N=C2N=NNN12)c1ccc(Cl)cc1

-20°C

12352200