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ProductsBack/hCG beta antibody [INN-hCG-68]

hCG beta antibody [INN-hCG-68]

GTX11391
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ELISA, RadioImmunoAssay
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetCGB3
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Overview

  • Supplier
    GeneTex
  • Product Name
    hCG beta antibody [INN-hCG-68]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody recognizes the beta 7 epitope on hCG beta. It recognises free human chorionic gonadotrophin beta (hCG beta), but does not bind to holo-hGG, holo-hLH or free hLH beta.
  • Application Supplier Note
    ELISA: 1/1000-1/80,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ELISA, RadioImmunoAssay
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    INN-hCG-68
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1082
  • Target name
    CGB3
  • Target description
    chorionic gonadotropin subunit beta 3
  • Target synonyms
    CGB; CGB5; CGB7; CGB8; CG-beta; choriogonadotropin subunit beta 3; chorionic gonadotrophin chain beta; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin beta subunit 3; chorionic gonadotropin chain beta; chorionic gonadotropin, beta polypeptide; hCGB; LHB; luteinizing hormone beta subunit
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Urine reference intervals for human chorionic gonadotropin (hCG) isoforms by immunoextraction-tandem mass spectrometry to detect hCG use. Butch AW et al., 2018 Jun, Drug Test Anal
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  • Immunoextraction-tandem mass spectrometry method for measuring intact human chorionic gonadotropin, free beta-subunit, and beta-subunit core fragment in urine. Woldemariam GA et al., 2014 Aug, Clin Chem
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  • The position of the alpha and beta subunits in a single chain variant of human chorionic gonadotropin affects the heterodimeric interaction of the subunits and receptor-binding epitopes. Ben-Menahem D et al., 2001 Aug 10, J Biol Chem
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