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ProductsBack/HCG-beta (Pregnancy & Choriocarcinoma Marker) (rHCGb/54), CF640R conjugate, 0.1mg/mL [26628-22-8]
HCG-beta (Pregnancy & Choriocarcinoma Marker) (rHCGb/54), CF640R conjugate, 0.1mg/mL [26628-22-8]

HCG-beta (Pregnancy & Choriocarcinoma Marker) (rHCGb/54), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC402197
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetCGB3
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Overview

  • Supplier
    Biotium
  • Product Name
    HCG-beta (Pregnancy & Choriocarcinoma Marker) (rHCGb/54), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    rHCGb/54
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID1082
  • Target name
    CGB3
  • Target description
    chorionic gonadotropin subunit beta 3
  • Target synonyms
    CGB; CGB5; CGB7; CGB8; CG-beta; choriogonadotropin subunit beta 3; chorionic gonadotrophin chain beta; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin beta subunit 3; chorionic gonadotropin chain beta; chorionic gonadotropin, beta polypeptide; hCGB; LHB; luteinizing hormone beta subunit
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP01233
  • Protein Name
    Choriogonadotropin subunit beta 7
  • Scientific Description
    This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the I+/- and beta subunits. The I+/- subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203