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HCV-IN-7

T11548
TargetMol Chemicals
CAS Number1449756-86-8
Product group Chemicals
Molecular Weight768.92
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    HCV-IN-7
  • Delivery Days Customer
    107
  • CAS Number
    1449756-86-8
  • Category Supplier
    Chemical
  • Chemical Name
    HCV-IN-7
  • Molecular Formula
    C40H48N8O6S
  • Molecular Weight
    768.92
  • Scientific Description
    HCV-IN-7 is an orally active and potent pan-genotypic HCV NS5A inhibitor (IC50s: 3-47 pM). It shows a superior pan-genotypic profile and a good pharmacokinetic profile coupled with a favorable liver uptake.
  • Shelf life instruction
    3 years
  • SMILES
    C([C@@H](NC(OC)=O)[C@@H](C)C)(=O)N1[C@H](C=2NC(C=3SC=4C=5C(=CC(=CC5)C=6NC(=NC6)[C@H]7N(C([C@@H](NC(OC)=O)[C@H](C)C)=O)CCC7)C=CC4C3)=CN2)CCC1
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Ramdas V, et al. Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate. J Med Chem. 2019 Dec 12;62(23):10563-10582.