HD-TAC7

MedChem Express

HD-TAC7

10

Research Use Only

98.75

C33H32FN7O7

657.65

HD-TAC7 is a potent PROTAC HDAC degrader with IC 50 values of 3.6 microM, 4.2 microM and 1.1 microM for HDAC1, HDAC2 and HDAC3, respectively. HD-TAC7 can decreases NF-kappaB p65 in RAW 264.7 macrophages. HD-TAC7 can be used for the research of inflammatory diseases like asthma and chronic obstructive pulmonary disease (COPD) [1] .

NC1=CC(F)=CC=C1NC(C2=CC=C(C=C2)NC(CCCCNC(CNC3=C4C(N(C(C4=CC=C3)=O)C5CCC(NC5=O)=O)=O)=O)=O)=O

-20°C,2°C to 8°C

12352200