HDAC-IN-45 [2421122-61-2]
HY-150577
CAS Number2421122-61-2
Product group Chemicals
Molecular Weight502.93
Overview
- SupplierMedChem Express
- Product NameHDAC-IN-45 [2421122-61-2]
- Delivery Days Customer10
- CAS Number2421122-61-2
- CertificationResearch Use Only
- Molecular FormulaC25H20ClFN8O
- Molecular Weight502.93
- Scientific DescriptionHDAC-IN-45 (Compound 14) is a small molecule HDAC inhibitor and has anticancer activity, also can forms a hydrogen bond with residue Y303. HDAC-IN-45 (Compound 14) has substantial inhibitory effects towards HDAC1, 2 and 3 isoforms with IC50 values of 0.108, 0.585 and 0.563 microM respectively[1].
- SMILESO=C(NC1=CC=CC=C1N)C2=CC=C(CN3C=NC4=C(NC5=CC=C(F)C(Cl)=C5)N=C(N)N=C34)C=C2
- UNSPSC12352200