HDAC-IN-45

MedChem Express

HDAC-IN-45

10

Research Use Only

C25H20ClFN8O

502.93

HDAC-IN-45 (Compound 14) is a small molecule HDAC inhibitor and has anticancer activity, also can forms a hydrogen bond with residue Y303. HDAC-IN-45 (Compound 14) has substantial inhibitory effects towards HDAC1, 2 and 3 isoforms with IC 50 values of 0.108, 0.585 and 0.563 microM respectively [1] .

O=C(NC1=CC=CC=C1N)C2=CC=C(CN3C=NC4=C(NC5=CC=C(F)C(Cl)=C5)N=C(N)N=C34)C=C2

12352200