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HDAC-IN-7

HDAC-IN-7

T2025
TargetMol Chemicals
CAS Number743420-02-2
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Product group Chemicals
Molecular Weight390.41
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    HDAC-IN-7
  • Delivery Days Customer
    4
  • CAS Number
    743420-02-2
  • Category Supplier
    Chemical
  • Chemical Name
    HDAC-IN-7
  • Molecular Formula
    C22H19FN4O2
  • Molecular Weight
    390.41
  • Scientific Description
    HDAC-IN-7 (HBI-8000) (Chidamide impurity) is an impurity of Chidamide. Chidamide is a potent and orally bioavailable inhibitor of HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10).
  • Shelf life instruction
    3 years
  • SMILES
    N(C(=O)C1=CC=C(CNC(C=CC=2C=CC=NC2)=O)C=C1)C3=C(N)C=CC(F)=C3
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Gong K, et al. CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells. Biochem J. 2012 May 1;443(3):735-46.
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