HDAC1/CDK7-IN-1 [2987905-95-1]

TargetMol Chemicals

HDAC1/CDK7-IN-1 [2987905-95-1]

16

Chemical

Research Use Only

HDAC1/CDK7-IN-1

C33H32ClN7O4

626.11

HDAC1/CDK7-IN-1 (compound 8e) is a dual inhibitor of CDK7 and HDAC1, with IC50 values of 893 nM and 248 nM, respectively. It suppresses the proliferation of cancer cell lines such as MDA-MB-231, MCF-7, A549, and HCT-116, induces cell cycle arrest and apoptosis in HCT-116 cells, and impedes their migration [1].

3 years

O=C(NC=1C=CC=C(C1)NC=2N=CC(Cl)=C(N2)C3=CNC=4C=CC=CC43)C=5C=CC=C(C5)NC(=O)CCCCCCC(=O)NO

-20°C

51202000