HDAC2-IN-1

MedChem Express

HDAC2-IN-1 [2919691-32-8]

10

Research Use Only

C22H23ClN4OS

426.96

HDAC2-IN-1 (Compound 17) is a brain penetrant, orally active, competitive HDAC2 inhibitor with an IC50 of 0.5 microM[1]. HDAC2-IN-1 also inhibits HDAC1 and HDAC8 with IC50s of 1.61 microM and 0.98 microM, respectively[1].

ClC1=CC([C@@H]2C[C@H](C(N3CCN(CC3)C4=NC=CC5=C4SC=C5)=O)NC2)=CC=C1

12131703