HDAC3/6-IN-2 [2417510-17-7]

TargetMol Chemicals

HDAC3/6-IN-2 [2417510-17-7]

999

Chemical

Research Use Only

HDAC3/6-IN-2

C49H67N5O6

822.09

HDAC3/6-IN-2 (compound 15) is a dual inhibitor targeting HDAC6 and HDAC3, with IC50 values of 0.368 microM and 0.635 microM, respectively. This compound demonstrates antitumor effects by inducing apoptosis in cancer cells, reducing HDAC6 and HDAC3 levels, and increasing acetylation of H3 and alpha-tubulin [1].

3 years

[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@@]2([H])[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(=C[C@]21C)C#N)C(=O)N1CCN(CC1)c1ccc(NC(=O)CCCCCCC(=O)NO)cc1

-20°C

51202000