HDAC6 degrader-3 [2785404-83-1]

TargetMol Chemicals

HDAC6 degrader-3 [2785404-83-1]

999

Chemical

Research Use Only

HDAC6 degrader-3

C41H41F4N7O11

883.8

HDAC6 degrader-3, a selective and potent degrader of HDAC6 through ternary complex formation and the ubiquitin-proteasome pathway, exhibits a DC50 value of 19.4 nM. With IC50 values of 4.54 nM for HDAC6 and 0.647 microM for HDAC1, it effectively induces robust hyperacetylation of alpha-tubulin [1].

3 years

C(C(O)=O)(F)(F)F.O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCCCCC(NC=4C=C5C(=CC4)N(CC6=C(F)C=C(C(NO)=O)C=C6)C(C)=N5)=O)=O

-20°C

51202000