HDAC6-IN-13

MedChem Express

HDAC6-IN-13

10

Research Use Only

C23H22N4O

370.45

HDAC6-IN-13 (Compound 35m) is a potent, highly selective, orally active HDAC6 inhibitor with an IC50 of 0.019 microM. HDAC6-IN-13 also inhibits HDAC1, HDAC2 and HDAC3 with IC50s of 1.53, 2.06 and 1.03 microM, respectively. HDAC6-IN-13 shows significant BBB permeability and anti-inflammatory activity.

CCNNC(C1=CC=C(C=C1)CN2C3=CC=CC=C3C=CC4=C2C=NC=C4)=O

See Manual

12352200