HDAC6-IN-49
HY-169156
Molecular Weight457.54
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameHDAC6-IN-49
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC23H27N3O5S
- Molecular Weight457.54
- Scientific DescriptionHDAC6-IN-49 (Compound 3) is an inhibitor for HDAC with IC50 of 0.012 and 0.735 microM for HDAC6 and HDAC1. HDAC6-IN-49 also exhibits inhibitory activities against MAO-B, cholinesterase (ChE), histamine receptor (H3R) and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective efficacy on SH-SY5Y cell. HDAC6-IN-49 improves cognitive function and locomotor ability in Drosophila Parkinsons disease models and in C. elegans Alzheimers disease models[1].
- SMILESO=S(N1C2=CC=C(C=C2C=C1)OCCCN3CCCCC3)(C4=CC=C(C=C4)C(NO)=O)=O
- UNSPSC12352200