HDAC6/8/BRPF1-IN-1

TargetMol Chemicals

HDAC6/8/BRPF1-IN-1

65

2484255-65-2

Chemical

HDAC6/8/BRPF1-IN-1

C18H17N3O5S

387.41

HDAC6/8/BRPF1-IN-1 is a dual inhibitor that targets HDAC6, HDAC8, and the bromodomain and PHD finger containing protein 1 (BRPF1). It exhibits inhibitory activity against HDAC1, HDAC6, and HDAC8 with IC50 values of 797 nM, 344 nM, and 908 nM, respectively. In addition, it inhibits BRPF1 with a Kd value of 175.2 nM. This compound is utilized in cancer research [1].

3 years

CN1C=2C(=CC(NS(=O)(=O)C3=CC=C(C(NO)=O)C=C3)=CC2)C=C(C)C1=O

-20°

12352200