HDAC8-IN-13

MedChem Express

HDAC8-IN-13

9

Research Use Only

C10H10N2O3S

238.26

HDAC8-IN-13 is a novel histone deacetylase 8 (HDAC8) inhibitor with antiparasitic activity. HDAC8-IN-13 can effectively inhibit the acetyl-L-lysine deacetylase activity of schistosomes, affecting the parasites infectivity. HDAC8-IN-13 can induce apoptosis and cause the death of schistosome cells. Through a specific structural basis design, HDAC8-IN-13 exhibits reduced affinity for human HDACs, thereby enhancing its selectivity [1] .

O=C(C1=CC=C(SCCC(N2)=O)C2=C1)NO

12352200