HDAC8/BRPF1-IN-1 [2484255-85-6]

MedChem Express

HDAC8/BRPF1-IN-1 [2484255-85-6]

10

2484255-85-6

Research Use Only

C19H19N3O6S

417.44

HDAC8/BRPF1-IN-1 (Compound 23a) is a dual inhibitor of HDAC8 and BRPF1 with an IC50 of 443 nM against human HDAC8 and a Kd of 67 nM against human BRPF1. HDAC8/BRPF1-IN-1 shows low in vitro activity against HDAC1 and 6[1].

O=C(NO)C1=CC=C(OC)C(S(=O)(NC2=CC3=C(N(C)C(C(C)=C3)=O)C=C2)=O)=C1

12131703