hDHODH-IN-12

TargetMol Chemicals

hDHODH-IN-12

999

Chemical

Research Use Only

hDHODH-IN-12

C22H15F3N4O3

440.37

hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 microM. As the rate-limiting enzyme in the de novo synthesis of pyrimidines, critical for DNA/RNA synthesis, DHODH is localized within the inner membrane of human mitochondria. hDHODH-IN-12 is applicable in lung cancer research [1].

3 years

-20°C

51202000