Heregulin-1 / Neuregulin-1 (Breast and Urothelial Marker)(NRG1/2710), CF647 conjugate, 0.1mg/mL [26628-22-8]

Biotium

Heregulin-1 / Neuregulin-1 (Breast and Urothelial Marker)(NRG1/2710), CF647 conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

NRG1/2710

0.1 mg/ml

Other Conjugate

NRG1

neuregulin 1

acetylcholine receptor-inducing activity; ARIA; GGF; GGF2; glial growth factor 2; heregulin, alpha (45kD, ERBB2 p185-activator); HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; neu differentiation factor; NRG1-IT2; pro-neuregulin-1, membrane-bound isoform; pro-NRG1; sensory and motor neuron derived factor; SMDF

Mouse

IgG1

Pro-neuregulin-1, membrane-bound isoform

Heregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

2°C to 8°C

12352203