HFE Polyclonal Antibody
RD81225A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse
TargetHFE
Overview
- SupplierReddot Biotech
- Product NameHFE Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3077
- Target nameHFE
- Target descriptionhomeostatic iron regulator
- Target synonymshereditary hemochromatosis protein; hereditary hemochromatosis protein HLA-H; HFE1; HH; high Fe; HLA-H; MHC class I-like protein HFE; MVCD7; TFQTL2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203