HG-12-6 [2222354-57-4]

TargetMol Chemicals

HG-12-6 [2222354-57-4]

114

2222354-57-4

Chemical

Research Use Only

HG-12-6

C29H27F3N6O2S

580.62

HG-12-6 is a type II inhibitor of IRAK4, demonstrating preferential binding to unphosphorylated inactive IRAK4 (IC50: 165 nM) and modulating IRAK4 activity in autoimmunity and inflammation.

3 years

N(C(=O)C1CC1)C=2SC=3C(N2)=CC=C(N3)C4=CC(C(NC5=CC(C(F)(F)F)=C(CN6CCNCC6)C=C5)=O)=CC=C4

-20°C

12352200