HGF Protein, Human, Recombinant (hFc)

TargetMol Chemicals

HGF Protein, Human, Recombinant (hFc)

9

Research Use Only

>95%

The HGF single chain can be processed into the active form of disulfide-linked heterodimer of alpha and beta chain.The protein has a predicted MW of 79.6 kDa (after cleavage of the signal peptide). Due to glycosylation, the protein migrates to 60-65 ...

Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different insulin sensitive cell types; plays a key role in beta-cell homeostasis; and is capable of modulating the inflammatory response.HGF plays a central role in these metabolic disorders,HGF levels could be employed as a biomarker for disease status/progression, and HGF/c-Met signaling pathway modulators could effectively regulate IR and treat diabetes.

-20°C

12352200