HGFR/c-Met Protein, Cynomolgus, Recombinant (His)

TargetMol Chemicals

HGFR/c-Met Protein, Cynomolgus, Recombinant (His)

9

Research Use Only

The mature form of HGF R is a heterodimer which can be cleaved into alpha and beta chain. The protein has a predicted MW of 32.5 kDa (alpha chain) and 69.9 kDa (beta chain). Due to glycosylation, the protein migrates to 45-52 kDa (alpha chain) and ...

c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. HGFR/c-Met Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 32.5 kDa (alpha chain) and 69.9 kDa (beta chain) and the accession number is A0A2K5UM36.

-20°C

12352200