HIF-2alpha-IN-4 [882268-69-1]

MedChem Express

HIF-2alpha-IN-4 [882268-69-1]

10

882268-69-1

Research Use Only

99.96

C9H9N3O4S2

287.32

HIF-2alpha-IN-4 is a potent inhibitor of hypoxia inducible factor-2alpha (HIF-2alpha) translation, with an IC50 of 5 microM. HIF-2alpha-IN-4 decreases both constitutive and hypoxia-induced HIF-2alpha protein expression. HIF-2alpha-IN-4 links its 5UTR iron-responsive element to oxygen sensing[1].

O=C(C1=C(N/N=C(C#N)/S(=O)(C)=O)C=CS1)OC

2°C to 8°C

12131703