Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using HIF1 alpha Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using HIF1 alpha Polyclonal Antibody at dilution 1:60
HIF1A Polyclonal Antibody
E-AB-11289
Product group Antibodies
Overview
- SupplierElabscience
- Product NameHIF1A Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.6mg/ml
- Scientific DescriptionThis gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
- UNSPSC12352203