HIF2 alpha antibody

GeneTex

HIF2 alpha antibody - Orthogonal, Overexpression Validated

9

Specific for HIF-2 alpha/EPAS. Does not cross react with HIF-1 alpha.

Recommended Starting Dilutions:For WB: Use at a dilution of 1:100-1:3000. Recognizes a band at 118kDa.For IHC: Use at a dilution of 1:100. For ICC/IF: Use at a dilution of 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Epas1

endothelial PAS domain protein 1

bHLHe7; bHLHe73; endothelial PAS domain-containing protein 1; EPAS-1; HIF; Hif like protein; HIF1 alpha-like factor; HIF-1-alpha-like factor; HIF1alpha-like factor; HIF-2; HIF2A; HIF-2alpha; HIF-2-alpha; HIF2-alpha; HIF-related factor; HL; HLF; HLF (HIF1alpha-like factor); HR; HRF; hypoxia inducible transcription factor 2alpha; hypoxia-inducible factor 2-alpha; mHLF; MO; MOP2

Rabbit

IgG

Endothelial PAS domain-containing protein 1

Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-2 alpha is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF-1alpha functions primarily in extravascular tissues. HIF-2 alpha is also a potent activator of the tie-2 gene, which is known to be selectively expressed in endothelial cells. (1)

Fish, Human, Monkey, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203