Western Blot analysis of 1) Hela, 2) 3T3, 3) Raw264.7, 4) Rat brain, 5) Rat kidney using Histone H2B Monoclonal Antibody at dilution of 1:2000.
Western Blot analysis of 1) Hela, 2) 3T3, 3) Raw264.7, 4) Rat brain, 5) Rat kidney using Histone H2B Monoclonal Antibody at dilution of 1:2000.
Histone H2B Monoclonal Antibody
E-AB-22086
Product group Antibodies
Overview
- SupplierElabscience
- Product NameHistone H2B Monoclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. HIST1H2BB (Histone Cluster 1 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN.
- UNSPSC12352203