HIV-1 protease-IN-8 [2925287-55-2]

TargetMol Chemicals

HIV-1 protease-IN-8 [2925287-55-2]

86

Chemical

Research Use Only

HIV-1 protease-IN-8

C25H35N3O5S

489.63

HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme with an IC50 of 0.32 nM. It exhibits IC50 values of 0.29 microM for the wild-type HIV-1 (HIV-1 NL4-3) and 1.90 microM against a drug-resistant variant (HIV-1 MDR), indicating strong antiviral activity against both strains [1].

3 years

N(S(=O)(=O)C1=CC=C(O)C=C1)(C[C@H]([C@H](CC2=CC=CC=C2)NC(=O)[C@@H]3CCNC3)O)CC(C)C

-20°C

51202000