HKB99

MedChem Express

HKB99

10

Research Use Only

97.35

C23H18N2O6S

450.46

HKB99 is an allosteric inhibitor of phosphoglycerate mutase 1 ( PGAM1 ). HKB99 inhibits the formation of invasive pseudopodia and increases the level of PAI-2 in vitro. HKB99 increases the oxidative stress, activates JNK/c-Jun and suppresses AKT and ERK. HKB99 can be used for the research of non-small-cell lung cancer (NSCLC) [1] [2] .

O=C1C2=C(C=C(NS(C3=CC=C(N4CCC4)C=C3)(=O)=O)C(O)=C2O)C(C5=CC=CC=C51)=O

-20°C

12352200