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HLA-A (MHC I) (108-2C5), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC041095
Biotium
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetHLA-A
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Overview

  • Supplier
    Biotium
  • Product Name
    HLA-A (MHC I) (108-2C5), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    108-2C5
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID3105
  • Target name
    HLA-A
  • Target description
    major histocompatibility complex, class I, A
  • Target synonyms
    HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLAA; leukocyte antigen class I-A; MHC class I antigen HLA-A heavy chain
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP01889
  • Protein Name
    HLA class I histocompatibility antigen, B-7 alpha chain
  • Scientific Description
    HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. This MAb is useful for HLA molecular typing of peripheral blood leukocytes as well as a large number of leukemic cell lines. It reacts with an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, -A28, -A29, -A30, -A31 and -Aw33). Its epitope maps between aa65-to-aa80 of thealpha1 domain of the HLA-A. This MAb recognizes an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, A28, -A29, -A30, -A31 and -Aw33). Furthermore, by testing its reactivity with HLA-A2 natural variants and mutants, the importance of amino acid residues 79 and/or 80 of thealpha1 domain was demonstrated in the formation of an intralocus HLA-A determinant.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203