Bio-Connect

HLA-DQ Antibody (MHC II)

Research Use Only
ORB606900
Biorbyt
ReactivityHuman
Product group Antibodies
TargetHLA-DQA1
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    HLA-DQ Antibody (MHC II)
  • Delivery Days Customer
    16
  • Application Supplier Note
    Optimal dilution of the recombinant HLA-DQ antibody should be determined by the researcher.
  • Applications Supplier
    Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml for 30 min at RT FACS, IF, IHC-Fr
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HLA-DQA1/2866R
  • Conjugate
    Unconjugated
  • Gene ID3117
  • Target name
    HLA-DQA1
  • Target description
    major histocompatibility complex, class II, DQ alpha 1
  • Target synonyms
    CELIAC1; DC-1 alpha chain; DC-alpha; DQA1; DQ-A1; HLA class II histocompatibility antigen DQ alpha chain; HLA class II histocompatibility antigen, DQ alpha 1 chain; HLA-DCA; HLA-DQA; MHC class II antigen DQA1; MHC class II DQ alpha chain; MHC class II DQA1; MHC class II HLA-DQ-alpha-1; MHC class II protein; MHC HLA-DQ alpha; truncated MHC class II antigen
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP01906
  • Protein Name
    HLA class II histocompatibility antigen, DQ alpha 2 chain
  • Scientific Description
    Recognizes a DQ antigen, which is a dimer of 60kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203