HLA-DQ Antibody (MHC II)
ORB606900
ReactivityHuman
Product group Antibodies
TargetHLA-DQA1
Overview
- SupplierBiorbyt
- Product NameHLA-DQ Antibody (MHC II)
- Delivery Days Customer16
- Application Supplier NoteOptimal dilution of the recombinant HLA-DQ antibody should be determined by the researcher.
- Applications SupplierFlow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml for 30 min at RT FACS, IF, IHC-Fr
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHLA-DQA1/2866R
- ConjugateUnconjugated
- Gene ID3117
- Target nameHLA-DQA1
- Target descriptionmajor histocompatibility complex, class II, DQ alpha 1
- Target synonymsCELIAC1; DC-1 alpha chain; DC-alpha; DQA1; DQ-A1; HLA class II histocompatibility antigen DQ alpha chain; HLA class II histocompatibility antigen, DQ alpha 1 chain; HLA-DCA; HLA-DQA; MHC class II antigen DQA1; MHC class II DQ alpha chain; MHC class II DQA1; MHC class II HLA-DQ-alpha-1; MHC class II protein; MHC HLA-DQ alpha; truncated MHC class II antigen
- HostRabbit
- IsotypeIgG
- Protein IDP01906
- Protein NameHLA class II histocompatibility antigen, DQ alpha 2 chain
- Scientific DescriptionRecognizes a DQ antigen, which is a dimer of 60kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203