Western blot analysis of extracts of various cell lines using HLA-DRA Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using HLA-DRA Polyclonal Antibody at 1:1000 dilution.
HLA-DRA Polyclonal Antibody
E-AB-60353
Product group Antibodies
Overview
- SupplierElabscience
- Product NameHLA-DRA Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionHLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
- UNSPSC12352203