HLA-G antibody

Biorbyt

HLA-G antibody

16

Low Endotoxin, Azide free format. Product does not contain preservatives and is intended primarily for functional applications. Preservative containing buffers are available for IHC applications. Flow cytometry: Extracellular and intracellular staining; recommended dilution: 2 μg/ml; positive control: JEG-3 human choriocarcinoma epithelial cell line. Immunohistochemistry (frozen sections): Recommended dilution: 10 μg/ml, incubation: 20 min at 25°C; positive tissue: extravillous cytotrophoblast. ELISA: Recommended dilution: 1 μg/ml; positive control: JEG-3 human choriocarcinoma epithelial cell line. The antibody 87G has been tested as the capture antibody in a sandwich ELISA for analysis of human HLA-G in combination with antibody W6/32. Functional application: The antibody 87G blocks interaction of HLA-G with inhibitory receptors. ELISA, FC, IHC-Fr

Research Use Only

Monoclonal

87G

1 mg/ml

Unconjugated

HLA-G

major histocompatibility complex, class I, G

b2 microglobulin; HLA class I histocompatibility antigen, alpha chain G; HLA G antigen; HLA-G histocompatibility antigen, class I, G; MHC class I antigen G; MHC class Ib antigen; MHC-G; mutant MHC class I antigen; mutant MHC class Ib antigen

IgG2a

HLA class I histocompatibility antigen, alpha chain G

Mouse monoclonal antibody to HLA-G which is a member of the MHC class I family that is observed in trophoblasts. It involved in the presentation of foreign antigens to the immune system also participate in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells.

Human

-20°C,2°C to 8°C

12352203