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HLM006474

Research Use Only
S8963
Selleck Chemicals
Product group Chemicals
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    HLM006474
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    HLM006474 is a small molecule pan-E2F inhibitor that inhibits DNA binding to E2F4 with IC50 of 29.8 uM in A375 cells. HLM006474 induces a reduction in cell proliferation and an increase in apoptosis. The CDK/Rb/E2F pathway is commonly disrupted in lung cancer, and HLM006474 is shown to have efficacy in lung cancer.
  • UNSPSC
    12352200

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